Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10132083 | 0.86 | MAOA (0.47) | KMT2AHPGDEPHX1MAOALMNA | |
| SCHEMBL29952336 | 0.84 | LMNA (0.40) | KMT2AHPGDEPHX1MAOALMNA | |
| SCHEMBL4191188 | 0.78 | MAOA (0.47) | KMT2AHPGDEPHX1MAOALMNA | |
| SCHEMBL29951830 | 0.76 | OPRM1 (0.36) | LMNAALDH1A1 | |
| SCHEMBL10132042 | 0.75 | MAOA (0.40) | KMT2AHPGDEPHX1MAOALMNA | |
| SCHEMBL19002495 | 0.75 | EPHX2 (0.47) | KMT2AHPGDMAOAGAAALDH1A1 | |
| SCHEMBL19002619 | 0.74 | EPHX2 (0.46) | KMT2AEPHX1MAOALMNAGAA | |
| SCHEMBL29955423 | 0.73 | MCL1 (0.36) | KMT2ALMNA | |
| SCHEMBL854306 | 0.73 | MAOA (0.42) | MAOAGAAALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL854305 | 0.73 | MAOA (0.42) | MAOAGAAALDH1A1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |