Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952699 | 0.84 | KMT2A (0.43) | LMNAMAOAKMT2AHPGDALDH1A1 | |
| SCHEMBL10132083 | 0.82 | MAOA (0.47) | LMNAMAOAKMT2AHPGDALDH1A1 | |
| SCHEMBL10132042 | 0.78 | MAOA (0.40) | LMNAMAOAKMT2AHPGDALDH1A1 | |
| SCHEMBL29953331 | 0.77 | ALDH1A1 (0.33) | LMNAHPGDALDH1A1 | |
| SCHEMBL854305 | 0.75 | MAOA (0.42) | MAOAALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL854306 | 0.75 | MAOA (0.42) | MAOAALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL10132028 | 0.74 | ALDH1A1 (0.40) | MAOAKMT2AHPGDALDH1A1MAPT | |
| SCHEMBL4191188 | 0.74 | MAOA (0.47) | LMNAMAOAKMT2AHPGDALDH1A1 | |
| SCHEMBL29952363 | 0.74 | MCL1 (0.34) | HPGDALDH1A1 | |
| SCHEMBL29955601 | 0.72 | TSHR (0.35) | LMNAKMT2AHPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |