Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12629117 | 0.72 | PGK1 (0.38) | — | |
| SCHEMBL29954468 | 0.72 | IDH1 (0.35) | CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL1316919 | 0.69 | HTR1D (0.48) | HRH3RAPGEF4CYP11B1CYP11B2HTR1D | |
| SCHEMBL27995904 | 0.69 | HRH3 (0.54) | HRH3RAPGEF4CYP11B1CYP11B2HTR1D | |
| SCHEMBL12032123 | 0.69 | HRH3 (0.32) | HRH3RAPGEF4CYP11B1CYP11B2HTR1D | |
| SCHEMBL327084 | 0.67 | HRH3 (0.41) | HRH3RAPGEF4CYP11B1CYP11B2HTR1D | |
| SCHEMBL28489168 | 0.67 | HRH3 (0.41) | HRH3RAPGEF4CYP11B1CYP11B2HTR1D | |
| SCHEMBL29951023 | 0.67 | PGK1 (0.38) | ALDH1A1 | |
| SCHEMBL29953337 | 0.65 | TAAR1 (0.50) | KDM4EALDH1A1LMNAGAAMAPT | |
| Bromide SCHEMBL17647120 | 0.65 | RAPGEF4 (0.46) | HRH3RAPGEF4CYP11B1CYP11B2HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |