Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | AGXT | P21549 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561423 | 0.88 | ENPP2 (0.43) | DAOMAOAMAOBALDH1A1LMNA | |
| SCHEMBL29953808 | 0.88 | CA2 (0.43) | ORAI1ORAI2ORAI3TRPV6ALDH1A1 | |
| SCHEMBL15331023 | 0.79 | TDP1 (0.37) | DAOMAOAMAOBLMNA | |
| SCHEMBL29956566 | 0.79 | DHFR (0.38) | DAOMAOAMAOBALDH1A1LMNA | |
| SCHEMBL29955289 | 0.78 | CXCR2 (0.39) | DAOMAOAMAOBCXCR1CXCR2 | |
| SCHEMBL29952084 | 0.77 | CA1 (0.36) | ALDH1A1LMNA | |
| SCHEMBL29957325 | 0.74 | KMT2A (0.38) | DAOMAOBLMNA | |
| SCHEMBL2556147 | 0.74 | KMT2A (0.38) | DAOMAOBALDH1A1LMNA | |
| SCHEMBL29952150 | 0.73 | CXCR2 (0.37) | CXCR2 | |
| SCHEMBL15738778 | 0.72 | ENPP2 (0.44) | ORAI1ORAI2ORAI3TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |