SCHEMBL29952831

SCHEMBL29952831

CCN(C)c1ccc(C=O)cn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
ALDH1A3 P47895 2/20 0.46
ALDH3A1 P30838 1/20 0.46
CYP2A6 P11509 3/20 0.44
CYP2A13 Q16696 1/20 0.44
AOC3 Q16853 1/20 0.43
HCAR3 P49019 1/20 0.41
PIK3CD O00329 1/20 0.40
PIK3CA P42336 1/20 0.40
PIK3CB P42338 1/20 0.40
PI4KA P42356 1/20 0.40
PIK3CG P48736 1/20 0.40
PI4KB Q9UBF8 1/20 0.40
KDM4E B2RXH2 2/20 0.39
KCNJ1 P48048 1/20 0.39
TRPV1 Q8NER1 1/20 0.39
GBA1 P04062 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23171392 0.86 HCAR3 (0.58) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL19330155 0.83 ALDH1A1 (0.57) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL30369918 0.83 ALDH1A1 (0.57) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL30592797 0.82 KCNH2 (0.51) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL934755 0.82 KCNH2 (0.51) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL24605670 0.81 POLB (0.47) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL18693771 0.78 DGAT1 (0.43) ALDH1A1HCAR3KDM4ELMNAMAPT
SCHEMBL20797725 0.77 ALDH1A1 (0.42) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL20797769 0.77 ALDH3A1 (0.50) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL20797695 0.76 HCAR3 (0.57) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed