Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955967 | 0.87 | CA1 (0.39) | TSHRKMT2ACA1CA2 | |
| SCHEMBL29950515 | 0.81 | CA2 (0.53) | TSHRLMNAALDH1A1CA1CA2 | |
| SCHEMBL29950857 | 0.80 | CA1 (0.35) | CA1CA2 | |
| SCHEMBL29956933 | 0.79 | ZDHHC7 (0.56) | LMNAKMT2AMAPTHSD17B10CA1 | |
| SCHEMBL29668156 | 0.79 | ZDHHC7 (0.36) | LMNACA1CA2 | |
| SCHEMBL29956277 | 0.78 | GABRP (0.38) | TSHRKMT2ACA1CA2SLC1A1 | |
| SCHEMBL29954134 | 0.77 | TSHR (0.37) | TSHRLMNAALDH1A1KMT2AMAPT | |
| SCHEMBL11298327 | 0.77 | CA1 (0.42) | TSHRLMNAKMT2ACA1CA2 | |
| SCHEMBL11592937 | 0.75 | TSHR (0.58) | TSHRLMNAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL10425792 | 0.73 | TSHR (0.56) | TSHRLMNAALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |