SCHEMBL29952933

SCHEMBL29952933

O=Cc1ccc2c(F)cccc2c1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.43
KIF11 P52732 2/20 0.41
ALDH1A1 P00352 4/20 0.39
CYP2A6 P11509 5/20 0.39
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ERN1 O75460 1/20 0.37
RAB9A P51151 2/20 0.36
KDM4E B2RXH2 2/20 0.36
NPC1 O15118 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PTGS2 P35354 1/20 0.36
UNG P13051 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4108450 1.00 PTGER4 (0.43) PTGER4KIF11ALDH1A1CYP2A6HSD17B1
SCHEMBL29953436 0.85 PTGER4 (0.50) PTGER4KIF11ALDH1A1CYP2A6SMN1; SMN2
SCHEMBL5381553 0.85 PTGER4 (0.50) PTGER4KIF11ALDH1A1CYP2A6SMN1; SMN2
SCHEMBL1666511 0.78 KIF11 (0.42) KIF11ALDH1A1CYP2A6ERN1RAB9A
SCHEMBL28131156 0.78 KIF11 (0.42) KIF11ALDH1A1CYP2A6RAB9AKDM4E
SCHEMBL29952947 0.78 HPRT1 (0.42) KIF11ALDH1A1CYP2A6SMN1; SMN2ERN1
SCHEMBL5406345 0.77 ALDH1A1 (0.50) KIF11ALDH1A1CYP2A6RAB9AKDM4E
SCHEMBL29953349 0.77 CYP1A2 (0.57) KIF11ALDH1A1CYP2A6
SCHEMBL9098185 0.77 PLAU (0.53) KIF11ALDH1A1HSD17B1HSD17B2RAB9A
SCHEMBL9670965 0.77 CYP1A2 (0.57) KIF11ALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed