Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5381553 | 1.00 | PTGER4 (0.50) | PTGER4ALDH1A1SMN1; SMN2CYP2A6KIF11 | |
| SCHEMBL29952933 | 0.85 | PTGER4 (0.43) | PTGER4ALDH1A1SMN1; SMN2CYP2A6KIF11 | |
| SCHEMBL4108450 | 0.85 | PTGER4 (0.43) | PTGER4ALDH1A1SMN1; SMN2CYP2A6KIF11 | |
| SCHEMBL28187823 | 0.78 | ALDH1A1 (0.47) | PTGER4ALDH1A1SMN1; SMN2CYP2A6KIF11 | |
| SCHEMBL9883875 | 0.78 | KIF11 (0.42) | ALDH1A1CYP2A6KIF11KDM4ENPC1 | |
| SCHEMBL5617799 | 0.78 | ALDH1A1 (0.56) | ALDH1A1CYP2A6KIF11KDM4ENPC1 | |
| SCHEMBL29957506 | 0.77 | CTDSP1 (0.53) | ALDH1A1CYP2A6KIF11KDM4ENPC1 | |
| SCHEMBL4102305 | 0.77 | ALDH1A1 (0.50) | PTGER4ALDH1A1SMN1; SMN2CYP2A6KIF11 | |
| SCHEMBL29951748 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP2A6KIF11KDM4ENPC1 | |
| SCHEMBL3257311 | 0.77 | CYP2A6 (0.57) | ALDH1A1CYP2A6KIF11NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |