Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409591 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL2451551 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL2478161 | 0.82 | ALDH1A1 (0.45) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL14877176 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL2181314 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ALMNAERN1 | |
| SCHEMBL6015170 | 0.79 | TDP1 (0.46) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL3716769 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL26725771 | 0.78 | MT-CO2 (0.56) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL16955594 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL1532661 | 0.77 | ALDH1A1 (0.60) | ALDH1A1TDP1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |