Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952946 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL2451551 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL2478161 | 0.82 | ALDH1A1 (0.45) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL14877176 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL2181314 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ALMNAERN1 | |
| SCHEMBL6015170 | 0.79 | TDP1 (0.46) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL3716769 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL26725771 | 0.78 | MT-CO2 (0.56) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL16955594 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TDP1MEN1KMT2ATSHR | |
| SCHEMBL1532661 | 0.77 | ALDH1A1 (0.60) | ALDH1A1TDP1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3737680-A1 | OCTAHYDROPYRIDO[1,2-ALPHA]PYRAZINES AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2020-11-18 | — | — | EP | claimed |
| WO-2019134985-A1 | OCTAHYDROPYRIDO[1,2-ALPHA]PYRAZINES AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2019-07-11 | — | — | WO | claimed |
| EP-4680236-A2 | 3-ALKYLAMINE INDOLE ACTIVATORS OF SEROTONIN RECEPTORS | ATAI Therapeutics, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| US-20240398772-A1 | OXASPIRO DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | JIANGSU NHWA PHARMACEUTICAL CO., LTD (CN) | 2024-12-05 | — | — | US | disclosed |
| CN-115403570-B | Mu-opioid receptor agonist, preparation method thereof and application thereof in medicine field | 上海华汇拓医药科技有限公司 | 2024-10-22 | — | — | CN | disclosed |
| WO-2024192150-A2 | 3-ALKYLAMINE INDOLE ACTIVATORS OF SEROTONIN RECEPTORS | Atai Therapeutics Inc. (US) | 2024-09-19 | — | — | WO | disclosed |
| EP-4375286-A1 | OXASPIRO DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shujing Biopharma Co., Ltd (CN) | 2024-05-29 | — | — | EP | disclosed |
| CN-117751126-A | Oxaspiro derivative, preparation method and application thereof | 上海枢境生物科技有限公司 | 2024-03-22 | — | — | CN | disclosed |
| US-20230219897-A1 | PYRAZOLE MAGL INHIBITORS | H. LUNDBECK A/S (DK) | 2023-07-13 | — | — | US | disclosed |
| EP-4194452-A1 | AROMATIC COMPOUND AND APPLICATION THEREOF IN ANTITUMOR DRUG | Shanghai Zheye Biotechnology Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |
| US-11655217-B2 | Pyrazole MAGL inhibitors | H. LUNDBECK A/S (DK) | 2023-05-23 | — | — | US | disclosed |
| EP-0077854-A1 | Herbicidal halogenated aromatic aminooxyacetic acid compounds and methods of use | UNION CARBIDE CORPORATION (US) | 1983-05-04 | — | — | EP | disclosed |
| US-4376769-A | Substituted imidazo thiazoles thiazines, thiazepines and thiazocines | SCHERING CORPORATION (US) | 1983-03-15 | — | — | US | disclosed |
| EP-0011279-B1 | PROCESS FOR THE PREPARATION OF AROMATICALLY SUBSTITUTED ACETIC ACIDS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1982-05-05 | — | — | EP | disclosed |
| US-4268442-A | REACTING AN AROMATIC ALKEHYDE WITH A TRIHALOMETHANE AND AN ALKANETHIOL IN THE PRESENCE OF A BASE AND AN APROTIC SOLVENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1981-05-19 | — | — | US | disclosed |
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| EP-0011279-A1 | Process for the preparation of aromatically substituted acetic acids | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1980-05-28 | — | — | EP | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219897-A1 | PYRAZOLE MAGL INHIBITORS | MGLL, PNLIP, LPL | ALDH1A1 2448/4885TDP1 2067/4885MEN1 3845/4885 |
| US-20240398772-A1 | OXASPIRO DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | OGFR, OPRL1, OPRM1 | ALDH1A1 537/4885TDP1 4154/4885MEN1 4061/4885 |
| US-11655217-B2 | Pyrazole MAGL inhibitors | MGLL, PNLIP, LPL | ALDH1A1 2260/4885TDP1 1754/4885MEN1 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.