Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.50 |
| ▸ | TRPV6 | Q9H1D0 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956692 | 0.82 | MBTD1 (0.50) | TRPV6L3MBTL3L3MBTL1MBTD1TSHR | |
| SCHEMBL2557827 | 0.79 | HRH3 (0.65) | HRH3KDM4EALDH1A1L3MBTL3L3MBTL1 | |
| SCHEMBL15033014 | 0.79 | LTA4H (0.46) | HRH3KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL18580991 | 0.79 | HRH3 (0.67) | HRH3MEN1ALDH1A1KMT2A | |
| SCHEMBL24064074 | 0.78 | POLB (0.56) | HRH3TRPV6KDM4EMEN1ALDH1A1 | |
| SCHEMBL4285135 | 0.78 | LMNA (0.61) | HRH3TRPV6KDM4EMEN1ALDH1A1 | |
| SCHEMBL12688022 | 0.78 | KDM4E (0.56) | HRH3TRPV6KDM4EMEN1ALDH1A1 | |
| SCHEMBL2320439 | 0.78 | LMNA (0.61) | HRH3KDM4EALDH1A1 | |
| SCHEMBL27934011 | 0.78 | ALDH1A1 (0.62) | HRH3KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL1427526 | 0.78 | HRH3 (0.69) | HRH3KDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |