Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952991 | 0.83 | MAPT (0.60) | MAPTNPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL20335100 | 0.82 | ALDH1A1 (0.71) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29952966 | 0.82 | KMT2A (0.69) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3633396 | 0.81 | NPC1 (0.84) | MAPTNPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL29957192 | 0.81 | EPHX2 (0.58) | MAPTNPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL9191376 | 0.80 | MAOA (0.60) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL4426386 | 0.80 | F7 (0.64) | ITGB3 | |
| SCHEMBL16223190 | 0.80 | NAMPT (0.69) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| Phenylhydantoic Acid SCHEMBL333005 | 0.80 | ABAT (0.67) | NPC1RAB9ASMN1; SMN2TAAR1ALDH1A1 | |
| SCHEMBL24381812 | 0.79 | FPR2 (0.62) | NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |