Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | WNT3A | P56704 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4974507 | 1.00 | CES2 (0.61) | CES2SRD5A2CTNNB1WNT3AALDH1A1 | |
| SCHEMBL459555 | 0.82 | CES2 (0.55) | CES2LMNAP2RX1 | |
| SCHEMBL30758861 | 0.82 | CES2 (0.69) | CES2SRD5A2CTNNB1WNT3AALDH1A1 | |
| SCHEMBL2073691 | 0.81 | ACHE (0.72) | CES2SRD5A2CTNNB1WNT3AALDH1A1 | |
| SCHEMBL1712437 | 0.81 | CES2 (0.67) | CES2SRD5A2CTNNB1WNT3AALDH1A1 | |
| SCHEMBL744906 | 0.80 | CTNNB1 (0.62) | CES2SRD5A2CTNNB1WNT3AALDH1A1 | |
| SCHEMBL24239347 | 0.80 | CES2 (0.56) | CES2SRD5A2CTNNB1WNT3AALDH1A1 | |
| SCHEMBL10274701 | 0.79 | CES2 (0.65) | CES2SRD5A2CTNNB1WNT3AALDH1A1 | |
| SCHEMBL2379125 | 0.79 | CES2 (0.65) | CES2SRD5A2CTNNB1WNT3AALDH1A1 | |
| SCHEMBL716488 | 0.79 | CES2 (0.65) | CES2SRD5A2CTNNB1WNT3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |