Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5546096 | 0.78 | ALDH1A1 (0.41) | ERN1ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL29696057 | 0.77 | ERN1 (0.42) | ERN1ALDH1A1KDM4EGPR3MAPT | |
| SCHEMBL28010138 | 0.77 | ERN1 (0.42) | ERN1ALDH1A1KDM4EGPR3MAPT | |
| SCHEMBL11167720 | 0.74 | CYP1A2 (0.39) | ERN1ALDH1A1KDM4EGPR3MAPT | |
| SCHEMBL26523063 | 0.74 | CA2 (0.44) | ERN1ALDH1A1KDM4EGPR3MEN1 | |
| SCHEMBL29953935 | 0.74 | ERN1 (0.47) | ERN1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29955009 | 0.73 | PARP1 (0.42) | ENPP2ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL20346 | 0.72 | MAPT (0.52) | ERN1ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL29956251 | 0.72 | MAPT (0.52) | ERN1ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL29952634 | 0.71 | KDM4E (0.46) | ENPP2KDM4EPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |