Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 9/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 3/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL9731767 | 0.83 | ERN1 (0.39) | ERN1MEN1KMT2AKDM4EPARP1 | |
| SCHEMBL9731764 | 0.81 | MAPT (0.47) | ERN1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL23262666 | 0.79 | TRIM24 (0.42) | ERN1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL1398173 | 0.79 | CYP1A2 (0.46) | ERN1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL7283402 | 0.77 | MET (0.50) | ERN1NPC1RAB9AMAP4K4CDK8 | |
| SCHEMBL28010138 | 0.76 | ERN1 (0.42) | ERN1KMT2AKDM4ENPC1IDO1 | |
| SCHEMBL29696057 | 0.76 | ERN1 (0.42) | ERN1KMT2AKDM4ENPC1IDO1 | |
| SCHEMBL3244529 | 0.76 | MTNR1B (0.49) | ERN1KDM4ENPSR1TRIM24TRIM33 | |
| SCHEMBL29956482 | 0.75 | CCR1 (0.50) | ERN1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL8867238 | 0.74 | ERN1 (0.40) | ERN1MEN1KMT2ALMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |