Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.46 |
| ▸ | NCF1 | P14598 | 6/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1543566 | 1.00 | PIK3CA (0.46) | PIK3CAPIK3CDPIK3CBNCF1MTOR | |
| SCHEMBL1543989 | 0.79 | NCF1 (0.70) | PIK3CAPIK3CDPIK3CBNCF1MTOR | |
| SCHEMBL16549300 | 0.79 | GAA (0.53) | PIK3CAPIK3CDPIK3CBNCF1MTOR | |
| SCHEMBL5504565 | 0.76 | ALDH1A3 (0.56) | PIK3CAPIK3CDPIK3CBNCF1MTOR | |
| SCHEMBL28505160 | 0.76 | MAPKAPK2 (0.60) | PIK3CAPIK3CDPIK3CBNCF1MTOR | |
| SCHEMBL3836532 | 0.75 | NCF1 (0.67) | PIK3CAPIK3CDPIK3CBNCF1ADRB2 | |
| SCHEMBL30307430 | 0.75 | NCF1 (0.67) | PIK3CAPIK3CDPIK3CBNCF1ADRB2 | |
| SCHEMBL875670 | 0.74 | PIK3CA (0.57) | PIK3CAPIK3CDHSD17B10ALDH1A1 | |
| SCHEMBL29760133 | 0.74 | PIK3CA (0.57) | PIK3CAPIK3CDHSD17B10ALDH1A1 | |
| SCHEMBL16549301 | 0.74 | ALDH1A1 (0.57) | ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |