SCHEMBL29953333

SCHEMBL29953333

C[Si](C)(C)c1c(F)cc(B(O)O)cc1F

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.32
CA2 P00918 1/20 0.31
LPL P06858 1/20 0.31
LIPG Q9Y5X9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29955899 0.77
SCHEMBL17196032 0.73 CA2 (0.40) ENPP2CA2LPLLIPG
SCHEMBL29951169 0.73 ENPP2 (0.32) ENPP2CA2LPLLIPG
SCHEMBL177479 0.72 CES2 (0.42) ENPP2CA2
SCHEMBL28382564 0.72 RAPGEF4 (0.33)
SCHEMBL1277215 0.70 ERN1 (0.38) ENPP2
SCHEMBL28703625 0.70 CES2 (0.40) ENPP2CA2
SCHEMBL6193465 0.70 SELL (0.33)
SCHEMBL28824846 0.70 ENPP2 (0.33) ENPP2CA2LPLLIPG
SCHEMBL18282087 0.69 ENPP2 (0.40) ENPP2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed