SCHEMBL29953340

SCHEMBL29953340

O=[N+]([O-])c1cc(B(O)O)cc(C(F)(F)F)c1

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.44
ALDH1A1 P00352 2/20 0.43
CYP3A4 P08684 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
HIF1A Q16665 1/20 0.43
TXNRD1 Q16881 1/20 0.43
TXNRD3 Q86VQ6 1/20 0.43
TXNRD2 Q9NNW7 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
P2RX1 P51575 3/20 0.40
P2RX4 Q99571 1/20 0.40
P2RX7 Q99572 1/20 0.40
TMPRSS4 Q9NRS4 1/20 0.39
KIF11 P52732 2/20 0.38
PTPN5 P54829 1/20 0.37
CYP19A1 P11511 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18356980 0.83 MEN1 (0.47) ALDH1A1CYP3A4HPGDTSHRCYP19A1
SCHEMBL1996062 0.81 ALDH1A1 (0.55) ALDH1A1CYP3A4HPGDALOX15TSHR
SCHEMBL6330190 0.81 CYP19A1 (0.54) ALDH1A1CYP3A4HPGDALOX15TSHR
SCHEMBL1005841 0.81 TSHR (0.55) ALDH1A1CYP3A4HPGDALOX15TSHR
Hydrochloric Acid SCHEMBL28212666 0.79 TSHR (0.53) ALDH1A1CYP3A4HPGDALOX15TSHR
Hydrazine SCHEMBL28307217 0.77 TSHR (0.52) ALDH1A1CYP3A4HPGDALOX15TSHR
SCHEMBL16164272 0.77 MGLL (0.61) MGLL
SCHEMBL126169 0.77 MGLL (0.61) MGLLP2RX1
SCHEMBL30542893 0.77 ALDH1A1 (0.47) ALDH1A1CYP3A4HPGDALOX15TSHR
SCHEMBL22206136 0.77 CYP19A1 (0.40) ALDH1A1CYP3A4HPGDALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed