Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6330190 | 0.86 | CYP19A1 (0.54) | CYP19A1MEN1KMT2AHTTLMNA | |
| SCHEMBL1172437 | 0.79 | CYP19A1 (0.55) | CYP19A1MEN1KMT2AHTTLMNA | |
| SCHEMBL7203812 | 0.79 | CYP19A1 (0.62) | CYP19A1MEN1KMT2AHTTLMNA | |
| SCHEMBL12265205 | 0.78 | ALDH1A1 (0.47) | CYP19A1MEN1KMT2AHTTLMNA | |
| SCHEMBL3755068 | 0.77 | ACP1 (0.41) | CYP19A1MEN1KMT2AHTTLMNA | |
| SCHEMBL2016539 | 0.77 | ALDH1A1 (0.46) | CYP19A1HTTTSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL8297742 | 0.77 | TSHR (0.63) | CYP19A1MEN1KMT2AHTTLMNA | |
| Fluoride SCHEMBL27574861 | 0.77 | CYP19A1 (0.59) | CYP19A1MEN1KMT2AHTTLMNA | |
| SCHEMBL29953340 | 0.77 | MGLL (0.44) | CYP19A1TSHRCYP3A4ALDH1A1HIF1A | |
| Hydrochloric Acid SCHEMBL2683825 | 0.76 | ALDH1A1 (0.44) | CYP19A1HTTTSHRSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212833-B | Phenylpyridine derivatives and pharmaceutical compositions containing the same | 株式会社大熊制药 | 2022-09-06 | — | — | CN | disclosed |
| EP-3696176-B1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | DAE WOONG PHARMA (KR) | 2022-05-04 | — | — | EP | disclosed |
| US-11149019-B2 | Phenylpyridine derivative and pharmaceutical composition comprising the same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2021-10-19 | — | — | US | disclosed |
| EP-3696176-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Daewoong Pharmaceutical Co., Ltd. (KR) | 2020-08-19 | — | — | EP | disclosed |
| US-20200223821-A1 | Novel Phenylpyridine Derivative and Pharmaceutical Composition Comprising the Same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2020-07-16 | — | — | US | disclosed |
| CN-111212833-A | Novel phenylpyridine derivative and pharmaceutical composition comprising same | 株式会社大熊制药 | 2020-05-29 | — | — | CN | disclosed |
| CN-105837572-A | N-substituted phenylacrylamide derivative and its preparation method and purpose | 四川大学 | 2016-08-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200223821-A1 | Novel Phenylpyridine Derivative and Pharmaceutical Composition Comprising the Same | PDCD1, PDCD5, PDCD11 | CYP19A1 1580/4885MEN1 1860/4885KMT2A 1800/4885 |
| US-11149019-B2 | Phenylpyridine derivative and pharmaceutical composition comprising the same | DPYD, PDCD5, PDCD1 | CYP19A1 1349/4885MEN1 1552/4885KMT2A 2108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.