SCHEMBL29953414

SCHEMBL29953414

CN(Cc1cc(Br)cs1)c1ccc(C=O)o1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.50
ALDH1A1 P00352 3/20 0.46
HTT P42858 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
HSP90AA1 P07900 1/20 0.33
HSP90AB1 P08238 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
PDK1 Q15118 1/20 0.33
PDK2 Q15119 1/20 0.33
PDK3 Q15120 1/20 0.33
PDK4 Q16654 1/20 0.33
CYP2A6 P11509 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29957280 0.74 CYP2A6 (0.44) ALDH1A1L3MBTL1SLC6A4SLC6A3HSP90AA1
SCHEMBL29952071 0.72 SLC6A4 (0.38) ALDH1A1HTTSLC6A4SLC6A3HSP90AA1
SCHEMBL2561276 0.69 ALDH1A3 (0.41) ALDH1A1SLC6A4SLC6A3HSP90AA1HSP90AB1
SCHEMBL2561890 0.69 HSP90AA1 (0.36) GAAALDH1A1L3MBTL1SLC6A4SLC6A3
SCHEMBL2564442 0.69 HSP90AA1 (0.34) ALDH1A1SLC6A4SLC6A3HSP90AA1HSP90AB1
SCHEMBL2558971 0.69 HSP90AA1 (0.31) HSP90AA1HSP90AB1CYP2C9CYP2C19PDK1
SCHEMBL2560536 0.69 ALDH1A3 (0.40) ALDH1A1HSP90AA1HSP90AB1CYP2C9CYP2C19
SCHEMBL3048491 0.69 GAA (1.00) GAAALDH1A1HTTL3MBTL1CYP2C9
SCHEMBL29953784 0.67 PYCR1 (0.35) ALDH1A1SLC6A4SLC6A3HSP90AA1HSP90AB1
SCHEMBL29955747 0.67 GAA (0.56) GAAALDH1A1HTTL3MBTL1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed