Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | DDO | Q99489 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17728135 | 1.00 | MAPT (0.36) | MAPTENPP2CES2CES1LIPE | |
| SCHEMBL29950753 | 0.86 | MAPT (0.41) | MAPTENPP2LIPE | |
| SCHEMBL3639412 | 0.86 | MAPT (0.41) | MAPTENPP2LIPE | |
| SCHEMBL29595177 | 0.85 | MAPT (0.44) | MAPTENPP2LIPE | |
| SCHEMBL2399704 | 0.85 | MAPT (0.44) | MAPTENPP2LIPE | |
| SCHEMBL29618976 | 0.77 | CES2 (0.43) | CES2CES1ACHEDAODDO | |
| SCHEMBL5015496 | 0.77 | CES2 (0.43) | CES2CES1ACHEDAODDO | |
| SCHEMBL4384 | 0.76 | CES2 (0.43) | ENPP2CES2CES1ERN1ACHE | |
| SCHEMBL29399046 | 0.76 | CES2 (0.43) | ENPP2CES2CES1ERN1ACHE | |
| SCHEMBL115327 | 0.75 | ENPP2 (0.46) | MAPTENPP2CES2CES1LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |