Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRG | P23470 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.34 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953959 | 0.88 | RAB9A (0.41) | PTPRGMAOBPOLBNPC1RAB9A | |
| SCHEMBL2558088 | 0.87 | PTPRG (0.43) | PTPRGMAOBPOLBNPC1RAB9A | |
| SCHEMBL29951557 | 0.78 | RAB9A (0.43) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29956878 | 0.77 | MAOA (0.46) | MAOBPOLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2556038 | 0.76 | MEN1 (0.49) | MAOBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29957048 | 0.76 | MEN1 (0.47) | POLBRAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2562700 | 0.75 | DAO (0.40) | MAOBPOLBKMT2ATDP1L3MBTL1 | |
| SCHEMBL29952254 | 0.75 | DAO (0.40) | MAOBNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL29950694 | 0.75 | CXCR2 (0.40) | MAOBPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28023477 | 0.73 | POLB (0.61) | MAOBPOLBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |