Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956878 | 0.89 | MAOA (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2556038 | 0.88 | MEN1 (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29952254 | 0.84 | DAO (0.40) | MEN1KMT2ASMN1; SMN2RAB9ACYP3A4 | |
| SCHEMBL29955730 | 0.78 | HTT (0.39) | ALDH1A1SMN1; SMN2MAPTHTTRAB9A | |
| SCHEMBL2562700 | 0.78 | DAO (0.40) | KMT2AMAPTPOLBDAOGAA | |
| SCHEMBL29953959 | 0.77 | RAB9A (0.41) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL257779 | 0.77 | DAO (0.36) | SMN1; SMN2HTTRAB9ADAO | |
| SCHEMBL29953533 | 0.76 | PTPRG (0.37) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL257865 | 0.75 | LPL (0.43) | ALDH1A1HTTHPGDCYP3A4CYP2D6 | |
| SCHEMBL28818845 | 0.74 | MGAM (0.51) | KMT2AALDH1A1MAPTRAB9ADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |