Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952426 | 0.88 | LMNA (0.40) | LMNAKDM4EMAPTERN1MAPK14 | |
| SCHEMBL15332851 | 0.88 | ERN1 (0.38) | TNKS2KDM4EMAPTERN1DHODH | |
| SCHEMBL29955999 | 0.85 | TNKS2 (0.40) | TNKS2KDM4EALDH1A1MAPTERN1 | |
| SCHEMBL2556672 | 0.85 | MGAM (0.39) | MGAMGAASIMGAM2ERN1 | |
| SCHEMBL15331877 | 0.83 | ERN1 (0.38) | TNKS2KDM4EMAPTERN1DHODH | |
| SCHEMBL2554515 | 0.82 | ERN1 (0.39) | TNKS2KDM4EMAPTERN1DHODH | |
| SCHEMBL29956203 | 0.81 | ERN1 (0.42) | HPGDKDM4EMAPTERN1 | |
| SCHEMBL29953250 | 0.81 | MMP2 (0.46) | ALDH1A1MAPTGAADRD2HTR2A | |
| SCHEMBL29957654 | 0.80 | ALDH1A1 (0.39) | TNKS2LMNAHPGDALDH1A1MAPT | |
| SCHEMBL15330961 | 0.80 | ERN1 (0.37) | TNKS2HPGDKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |