Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954488 | 0.87 | SMN1; SMN2 (0.44) | MMP2MMP9MMP8MMP13MAPT | |
| SCHEMBL29952426 | 0.84 | LMNA (0.40) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL29957073 | 0.81 | SMN1; SMN2 (0.50) | MMP2MMP9MMP8MMP13MAPT | |
| SCHEMBL29953933 | 0.81 | MAPT (0.48) | MMP2MMP9MMP8MMP13MAPT | |
| SCHEMBL2556672 | 0.81 | MGAM (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL29953545 | 0.81 | TNKS2 (0.44) | MAPTALDH1A1DRD2HTR2AHTR2C | |
| SCHEMBL15330037 | 0.80 | MMP2 (0.50) | MMP2MMP9MMP8MMP13MAPT | |
| SCHEMBL15333187 | 0.79 | MAPT (0.47) | MMP2MMP9MMP8MMP13MAPT | |
| SCHEMBL2557296 | 0.78 | GRIN2D (0.41) | MAPTALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL29956203 | 0.77 | ERN1 (0.42) | MAPTRAB9APOLBGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |