Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.60 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.57 |
| ▸ | ERN1 | O75460 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.52 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | TLR2 | O60603 | 1/20 | 0.52 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.52 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.52 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1647101 | 1.00 | BACE1 (0.60) | BACE1CAPN1ERN1ALDH1A1TDP1 | |
| SCHEMBL19792588 | 0.85 | ERN1 (0.71) | ERN1ALDH1A1KDM4EMAPT | |
| SCHEMBL37462 | 0.84 | ALDH1A1 (0.63) | CAPN1ERN1ALDH1A1TDP1TSHR | |
| SCHEMBL4034867 | 0.79 | ALDH1A1 (0.51) | BACE1CAPN1ERN1ALDH1A1TSHR | |
| SCHEMBL6703981 | 0.79 | CYP3A4 (0.44) | BACE1CAPN1ERN1ALDH1A1TDP1 | |
| SCHEMBL20152991 | 0.78 | BACE1 (0.77) | BACE1CAPN1ALDH1A1TDP1KDM4E | |
| SCHEMBL9560068 | 0.78 | NR5A1 (0.51) | ALDH1A1HPGD | |
| SCHEMBL1662997 | 0.78 | ALDH1A1 (0.70) | ALDH1A1TDP1TSHRKDM4ETRIM24 | |
| SCHEMBL29392394 | 0.78 | ALDH1A1 (0.71) | ERN1ALDH1A1TDP1TSHRKDM4E | |
| SCHEMBL419596 | 0.78 | ALDH1A1 (0.57) | ERN1ALDH1A1TDP1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680039-A1 | COMPOSITIONS FOR REDUCING OFF NOTES AND USES THEREOF | DSM-Firmenich AG (CH) | 2026-01-21 | — | — | EP | disclosed |
| US-20250353874-A1 | GLUCOCORTICOID RECEPTOR AGONISTS | LILLY CO ELI (US) | 2025-11-20 | — | — | US | disclosed |
| US-12404298-B2 | Glucocorticoid receptor agonists | ELI LILLY AND COMPANY (US) | 2025-09-02 | — | — | US | disclosed |
| WO-2024251755-A1 | COMPOSITIONS FOR REDUCING OFF NOTES AND USES THEREOF | DSM-FIRMENICH AG (CH) | 2024-12-12 | — | — | WO | disclosed |
| US-20240018182-A1 | GLUCOCORTICOID RECEPTOR AGONISTS | ELI LILLY AND COMPANY | 2024-01-18 | — | — | US | disclosed |
| US-11787834-B2 | Glucocorticoid receptor agonists | ELI LILLY AND COMPANY (US) | 2023-10-17 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-20220324904-A1 | GLUCOCORTICOID RECEPTOR AGONISTS | ELI LILLY AND COMPANY | 2022-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12404298-B2 | Glucocorticoid receptor agonists | NR3C1, NR3C2, MC2R | BACE1 2495/4885CAPN1 3943/4885ERN1 1650/4885 |
| US-20240018182-A1 | GLUCOCORTICOID RECEPTOR AGONISTS | NR3C1, NR3C2, MC2R | BACE1 2495/4885CAPN1 3943/4885ERN1 1650/4885 |
| US-20250353874-A1 | GLUCOCORTICOID RECEPTOR AGONISTS | NR3C1, NR3C2, MC2R | BACE1 2495/4885CAPN1 3943/4885ERN1 1650/4885 |
| US-11787834-B2 | Glucocorticoid receptor agonists | NR3C1, NR3C2, MC2R | BACE1 2495/4885CAPN1 3943/4885ERN1 1650/4885 |
| US-20220324904-A1 | GLUCOCORTICOID RECEPTOR AGONISTS | NR3C1, NR3C2, MC2R | BACE1 2495/4885CAPN1 3943/4885ERN1 1650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.