Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562063 | 0.86 | ALDH1A1 (0.48) | PTGS2ALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL2560074 | 0.86 | KMT2A (0.56) | PTGS2ALDH1A1KMT2ASMN1; SMN2CYP2C9 | |
| SCHEMBL2558113 | 0.86 | KDM4E (0.49) | PTGS2ALDH1A1KMT2ASMN1; SMN2CYP2C9 | |
| SCHEMBL2558976 | 0.86 | PTGS2 (0.60) | PTGS2ALDH1A1KMT2ASMN1; SMN2CYP2C9 | |
| SCHEMBL15330476 | 0.85 | PKM (0.51) | PTGS2ALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL2560709 | 0.84 | SMN1; SMN2 (0.53) | PTGS2ALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL2561726 | 0.84 | KMT2A (0.60) | PTGS2ALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL2561958 | 0.82 | PTGS2 (0.41) | PTGS2ALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL15330652 | 0.82 | RAB9A (0.42) | PTGS2ALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL2555928 | 0.82 | MEN1 (0.59) | PTGS2ALDH1A1KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |