Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1528987 | 1.00 | NR1I2 (0.42) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL29951465 | 0.83 | KIF11 (0.44) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL8925344 | 0.81 | ALDH1A1 (0.59) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL536190 | 0.79 | IDO1 (0.42) | MGLL | |
| SCHEMBL3205095 | 0.79 | SMN1; SMN2 (0.43) | HTTKIF11ARMGLL | |
| SCHEMBL29349652 | 0.79 | CES2 (0.50) | KIF11ARMGLL | |
| SCHEMBL29951765 | 0.79 | SMN1; SMN2 (0.43) | HTTKIF11ARMGLL | |
| SCHEMBL29825643 | 0.79 | IDO1 (0.42) | MGLL | |
| SCHEMBL496773 | 0.79 | CES2 (0.50) | KIF11ARMGLL | |
| SCHEMBL3785258 | 0.78 | TSHR (0.55) | ALDH1A1HSD17B10KIF11ARENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |