Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | TYR | P14679 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | MIF | P14174 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.41 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1528987 | 0.81 | NR1I2 (0.42) | ALDH1A1TYRALOX15LMNAHSD17B10 | |
| SCHEMBL29953597 | 0.81 | NR1I2 (0.42) | ALDH1A1TYRALOX15LMNAHSD17B10 | |
| SCHEMBL27201659 | 0.78 | ALDH1A1 (0.45) | ALDH1A1TYRALOX15LMNAHSD17B10 | |
| SCHEMBL14994054 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TYRALOX15LMNAHSD17B10 | |
| SCHEMBL24425189 | 0.77 | ENPP2 (0.38) | ALDH1A1TYRALOX15LMNAHSD17B10 | |
| SCHEMBL3783736 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TYRALOX15LMNAHSD17B10 | |
| SCHEMBL24425181 | 0.77 | PTGS1 (0.41) | ALDH1A1TYRALOX15LMNAHSD17B10 | |
| SCHEMBL2160202 | 0.77 | ALDH1A1 (0.70) | ALDH1A1TYRALOX15LMNAHSD17B10 | |
| E319 SCHEMBL29350903 | 0.75 | ALDH1A1 (1.00) | ALDH1A1TYRALOX15LMNAHSD17B10 | |
| E319 SCHEMBL26745 | 0.75 | ALDH1A1 (1.00) | ALDH1A1TYRALOX15LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622962-A | PROSTATE CANCER, SKIN DISORDERS, BALDNESS | ELI LILLY AND COMPANY (US) | 1997-04-22 | — | — | US | disclosed |
| US-5578724-A | INHIBITORS OF 5-ALPHA-REDUCTASE | ELI LILLY AND COMPANY (US) | 1996-11-26 | — | — | US | disclosed |
| WO-1996035422-A1 | METHODS FOR INHIBITING BONE LOSS | ELI LILLY AND COMPANY (US) | 1996-11-14 | — | — | WO | disclosed |