Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437878 | 0.81 | L3MBTL1 (0.58) | POLBL3MBTL1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL5376069 | 0.80 | TLR7 (0.45) | POLBMETAP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL30441012 | 0.80 | KDM4E (0.46) | POLBMETAP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL28085307 | 0.80 | L3MBTL1 (0.41) | POLBMETAP1L3MBTL1ALDH1A1LMNA | |
| Ammonia Solution, Strong SCHEMBL28013995 | 0.79 | KDM4E (0.44) | POLBMETAP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL21358025 | 0.79 | GABRA1 (0.42) | POLBMETAP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL2414354 | 0.79 | POLB (0.44) | POLBMETAP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL27593401 | 0.79 | GRM4 (0.41) | POLBMETAP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL30322596 | 0.79 | L3MBTL1 (0.41) | POLBMETAP1L3MBTL1ALDH1A1LMNA | |
| Tert-Butanol SCHEMBL25377982 | 0.77 | KDM4E (0.43) | POLBMETAP1L3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |