Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953673 | 0.81 | POLB (0.40) | L3MBTL1ALOX15ALDH1A1KDM4ENPSR1 | |
| SCHEMBL18705823 | 0.80 | L3MBTL1 (0.46) | L3MBTL1ALOX15MAP2K1HTTALDH1A1 | |
| SCHEMBL69177 | 0.79 | L3MBTL1 (0.64) | L3MBTL1ALOX15MAP2K1HTTALDH1A1 | |
| SCHEMBL29416324 | 0.78 | L3MBTL1 (0.62) | L3MBTL1ALOX15MAP2K1HTTALDH1A1 | |
| SCHEMBL69990 | 0.78 | L3MBTL1 (0.62) | L3MBTL1ALOX15MAP2K1HTTALDH1A1 | |
| SCHEMBL108876 | 0.78 | L3MBTL1 (0.62) | L3MBTL1ALOX15MAP2K1HTTALDH1A1 | |
| SCHEMBL128711 | 0.78 | L3MBTL1 (0.62) | L3MBTL1ALOX15MAP2K1HTTALDH1A1 | |
| SCHEMBL31347575 | 0.78 | L3MBTL1 (0.62) | L3MBTL1ALOX15MAP2K1HTTALDH1A1 | |
| SCHEMBL2561503 | 0.77 | L3MBTL1 (0.57) | L3MBTL1ALOX15MAP2K1HTTALDH1A1 | |
| SCHEMBL3461964 | 0.77 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1KDM4ETDP1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117534613-A | Preparation method of 3-aminopyridine-2-carboxylic acid methyl ester | 武威广达科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| EP-2124913-A1 | 1-AMINOMETHYL- L- PHENYL- CYCLOHEXANE DERIVATIVES AS DDP-IV INHIBITORS | Novartis AG (CH) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008077597-A1 | 1-AMINOMETHYL- L- PHENYL- CYCLOHEXANE DERIVATIVES AS DDP-IV INHIBITORS | NOVARTIS AG (CH) | 2008-07-03 | — | — | WO | disclosed |