Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953018 | 0.91 | MEN1 (0.52) | SMYD3L3MBTL1AKR1C3MEN1KMT2A | |
| SCHEMBL29958499 | 0.89 | MAPK1 (0.54) | SMYD3L3MBTL1AKR1C3MEN1KMT2A | |
| SCHEMBL7845382 | 0.78 | PKM (0.60) | L3MBTL1MEN1KMT2AEGLN1 | |
| SCHEMBL19058454 | 0.78 | SMYD3 (0.51) | SMYD3L3MBTL1AKR1C3MEN1KMT2A | |
| SCHEMBL29191072 | 0.77 | MEN1 (0.70) | SMYD3AKR1C3MEN1KMT2AALDH1A1 | |
| SCHEMBL14843674 | 0.75 | SMYD3 (0.49) | SMYD3L3MBTL1AKR1C3MEN1KMT2A | |
| SCHEMBL14843672 | 0.75 | SMYD3 (0.49) | SMYD3L3MBTL1AKR1C3MEN1KMT2A | |
| SCHEMBL2644934 | 0.74 | CA1 (0.61) | L3MBTL1ALDH1A1POLB | |
| SCHEMBL29955250 | 0.74 | SMYD3 (0.47) | SMYD3L3MBTL1AKR1C3MEN1KMT2A | |
| SCHEMBL20748619 | 0.73 | EGLN1 (0.35) | SMYD3L3MBTL1MEN1KMT2AEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |