Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958499 | 0.94 | MAPK1 (0.54) | MEN1KMT2AALDH1A1L3MBTL1AKR1C3 | |
| SCHEMBL29953684 | 0.91 | SMYD3 (0.51) | MEN1KMT2AALDH1A1L3MBTL1AKR1C3 | |
| SCHEMBL29957012 | 0.74 | ITGB3 (0.44) | MEN1KMT2AALDH1A1SMYD3POLB | |
| SCHEMBL29191072 | 0.74 | MEN1 (0.70) | MEN1KMT2AALDH1A1AKR1C3SMYD3 | |
| SCHEMBL14843672 | 0.73 | SMYD3 (0.49) | MEN1KMT2AALDH1A1L3MBTL1AKR1C3 | |
| SCHEMBL5655124 | 0.73 | MAPK1 (0.68) | MEN1KMT2AALDH1A1FABP4POLB | |
| SCHEMBL18409238 | 0.72 | FABP4 (0.77) | ALDH1A1FABP4POLBMAPK1KDM4E | |
| SCHEMBL29955250 | 0.71 | SMYD3 (0.47) | MEN1KMT2AALDH1A1L3MBTL1AKR1C3 | |
| SCHEMBL8284047 | 0.70 | TDP1 (0.58) | MEN1KMT2AALDH1A1L3MBTL1AKR1C3 | |
| SCHEMBL29957675 | 0.70 | SMYD3 (0.40) | MEN1KMT2AALDH1A1L3MBTL1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |