Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953018 | 0.94 | MEN1 (0.52) | MAPK1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL29953684 | 0.89 | SMYD3 (0.51) | MEN1KMT2APOLBALDH1A1AKR1C3 | |
| SCHEMBL5655124 | 0.80 | MAPK1 (0.68) | MAPK1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL27563409 | 0.73 | LMNA (0.68) | MAPK1POLBSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL14088976 | 0.73 | HDAC3 (0.74) | MAPK1CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL24316125 | 0.72 | MAPK1 (0.76) | MAPK1POLBSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL29957012 | 0.72 | ITGB3 (0.44) | MEN1KMT2APOLBALDH1A1SMYD3 | |
| SCHEMBL29191072 | 0.72 | MEN1 (0.70) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL428355 | 0.71 | MAPK1 (1.00) | MAPK1POLBSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL18912261 | 0.70 | CYP1A2 (0.55) | MAPK1POLBSMN1; SMN2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |