Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | LPL | P06858 | 2/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968323 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KMT2ATSHRFBP1LPL | |
| SCHEMBL5706236 | 0.96 | LMNA (0.52) | ALDH1A1KMT2ATSHRLPLLIPG | |
| SCHEMBL934547 | 0.84 | KMT2A (0.47) | ALDH1A1KMT2ATSHRLPLLIPG | |
| SCHEMBL29953841 | 0.83 | CYP2C19 (0.61) | ALDH1A1KMT2ALMNASMN1; SMN2KDM4E | |
| SCHEMBL520372 | 0.83 | CYP2C19 (0.61) | ALDH1A1KMT2ALMNASMN1; SMN2KDM4E | |
| SCHEMBL8064506 | 0.83 | LMNA (0.55) | ALDH1A1KMT2ATSHRLMNAHTT | |
| SCHEMBL20202315 | 0.81 | ALDH1A1 (0.66) | ALDH1A1KMT2ATSHRFBP1LMNA | |
| SCHEMBL21988575 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KMT2AFBP1LMNASMN1; SMN2 | |
| SCHEMBL8548241 | 0.80 | KMT2A (0.78) | ALDH1A1KMT2ATSHRFBP1LMNA | |
| SCHEMBL922624 | 0.79 | PRMT1 (0.62) | ALDH1A1KMT2ATSHRFBP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |