Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | LPL | P06858 | 2/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953713 | 0.96 | ALDH1A1 (0.56) | LMNAMAPK1HTTALDH1A1LPL | |
| SCHEMBL3968323 | 0.96 | ALDH1A1 (0.56) | LMNAMAPK1HTTALDH1A1LPL | |
| SCHEMBL934547 | 0.83 | KMT2A (0.47) | LMNAMAPK1HTTALDH1A1LPL | |
| SCHEMBL1465414 | 0.82 | LMNA (0.55) | LMNAMAPK1HTTALDH1A1EPHX2 | |
| SCHEMBL21988575 | 0.82 | ALDH1A1 (0.49) | LMNAALDH1A1EPHX2KMT2APKM | |
| SCHEMBL520372 | 0.82 | CYP2C19 (0.61) | LMNAALDH1A1KMT2APKMKDM4E | |
| SCHEMBL29953841 | 0.82 | CYP2C19 (0.61) | LMNAALDH1A1KMT2APKMKDM4E | |
| SCHEMBL31014170 | 0.81 | LMNA (0.56) | LMNAMAPK1HTTALDH1A1TSHR | |
| SCHEMBL11706540 | 0.81 | KMT2A (0.76) | LMNAMAPK1HTTALDH1A1EPHX2 | |
| SCHEMBL11704757 | 0.79 | KMT2A (0.73) | LMNAMAPK1HTTALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562961-B1 | HALO SULFONYL ARYL BORONATES | NOVO NORDISK AS (DK) | 2006-10-25 | — | — | EP | disclosed |
| EP-1562961-A1 | HALO SULFONYL ARYL BORONATES | NOVO NORDISK A/S (DK) | 2005-08-17 | — | — | EP | disclosed |
| US-6872849-B2 | Halo sulfonyl aryl boronates | NOVO NORDISK A/S (DK) | 2005-03-29 | — | — | US | disclosed |
| US-20040116701-A1 | Halo sulfonyl aryl boronates | NOVO NORDISK A/S (DK) | 2004-06-17 | — | — | US | disclosed |
| WO-2004041833-A1 | HALO SULFONYL ARYL BORONATES | NOVO NORDISK A/S (DK) | 2004-05-21 | — | — | WO | disclosed |