Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | PKM | P14618 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL520372 | 1.00 | CYP2C19 (0.61) | CYP2C19ALDH1A1PKMGAAKMT2A | |
| SCHEMBL7623885 | 0.86 | CYP2C19 (0.73) | CYP2C19ALDH1A1PKMGAAKMT2A | |
| SCHEMBL3968323 | 0.83 | ALDH1A1 (0.56) | CYP2C19ALDH1A1PKMGAAKMT2A | |
| SCHEMBL29953713 | 0.83 | ALDH1A1 (0.56) | CYP2C19ALDH1A1PKMGAAKMT2A | |
| SCHEMBL9121912 | 0.83 | CYP2C19 (0.69) | CYP2C19ALDH1A1PKMGAAKMT2A | |
| SCHEMBL934547 | 0.82 | KMT2A (0.47) | CYP2C19ALDH1A1KMT2ABRD4MEN1 | |
| SCHEMBL5706236 | 0.82 | LMNA (0.52) | CYP2C19ALDH1A1PKMKMT2AMEN1 | |
| SCHEMBL18995906 | 0.81 | CYP2C19 (0.67) | CYP2C19ALDH1A1PKMGAAKMT2A | |
| SCHEMBL387555 | 0.81 | ALDH1A1 (0.60) | CYP2C19ALDH1A1PKMGAAKMT2A | |
| SCHEMBL28175168 | 0.79 | CYP2C19 (0.56) | CYP2C19ALDH1A1PKMGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024186839-A1 | BICYCLIC ARYL SULFONAMIDES, SULFONES, AND SULFONATE ESTERS AS ANTI-PARASITIC AGENTS | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2024-09-12 | — | — | WO | disclosed |
| CN-113840820-B | Phthalazinone compounds and uses thereof | ST制药株式会社 | 2024-05-03 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |