Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057139 | 0.81 | TP53 (0.44) | TERTACHEMAPTNPSR1ALDH1A1 | |
| SCHEMBL8284593 | 0.79 | ACHE (0.39) | TERTACHEMAPTHTTALDH1A1 | |
| SCHEMBL6871053 | 0.79 | ACHE (0.39) | TERTACHEALDH1A1MAOAMAOB | |
| SCHEMBL8295933 | 0.78 | ACHE (0.38) | TERTACHEMAPTHTTALDH1A1 | |
| SCHEMBL11098422 | 0.78 | ACHE (0.43) | TERTACHEMAPTHTTHPGD | |
| SCHEMBL28367550 | 0.77 | ACHE (0.50) | ACHEMAPTHTTHPGDALDH1A1 | |
| SCHEMBL30753697 | 0.77 | ALDH1A1 (0.50) | ACHEMAPTHTTHPGDALDH1A1 | |
| SCHEMBL21183204 | 0.77 | TYR (0.40) | MAPTHTTHPGDALDH1A1MAOA | |
| SCHEMBL911004 | 0.77 | MTNR1A (0.52) | TERTACHEMAOAMAOBCYP1A2 | |
| SCHEMBL10144174 | 0.76 | ACHE (0.44) | ACHEHPGDALDH1A1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |