SCHEMBL10144174

SCHEMBL10144174

CCCSc1cccc(C)c1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.44
APLNR P35414 1/20 0.42
MAOA P21397 2/20 0.42
MAOB P27338 2/20 0.42
AR P10275 2/20 0.40
ALDH1A1 P00352 4/20 0.39
MAPK1 P28482 3/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA13 Q8N1Q1 1/20 0.39
POLB P06746 1/20 0.38
DHFR P00374 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
HPGD P15428 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30753697 0.89 ALDH1A1 (0.50) ACHEMAOAMAOBALDH1A1MAPK1
SCHEMBL425169 0.88 MAOA (0.45) ACHEMAOAMAOBARALDH1A1
SCHEMBL13397723 0.87 MAOA (0.47) MAOAMAOBARALDH1A1MAPK1
SCHEMBL5168941 0.85 ACHE (0.46) ACHEMAOAMAOBALDH1A1MAPK1
SCHEMBL17277336 0.83 KIF11 (0.49) ACHEMAOAMAOBALDH1A1MAPK1
SCHEMBL709584 0.83 ACHE (0.48) ACHEMAOAMAOBALDH1A1MAPK1
SCHEMBL29722802 0.83 ACHE (0.48) ACHEMAOAMAOBALDH1A1MAPK1
SCHEMBL7595204 0.82 ACHE (0.42) ACHEMAOAMAOBALDH1A1MAPK1
SCHEMBL4184128 0.82 ACHE (0.42) ACHEMAOAMAOBALDH1A1MAPK1
SCHEMBL28367550 0.80 ACHE (0.50) ACHEMAOAMAOBALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11072632-B2 Inhibitors of 17β-HSD1, 17β-HSD3 and 17β-HSD10 UNIVERSITé LAVAL (CA) 2021-07-27 US disclosed
US-8828629-B2 Black curable composition, light-shielding color filter for a solid-state imaging device and method of producing the same, solid-state imaging device, wafer level lens, and camera module FUJIFILM CORPORATION (JP) 2014-09-09 US disclosed
US-8828629-B2 Black curable composition, light-shielding color filter for a solid-state imaging device and method of producing the same, solid-state imaging device, wafer level lens, and camera module FUJIFILM CORPORATION (JP) 2014-09-09 US disclosed
US-20130028587-A1 BLACK CURABLE COMPOSITION, LIGHT-SHIELDING COLOR FILTER FOR A SOLID-STATE IMAGING DEVICE AND METHOD OF PRODUCING THE SAME, SOLID-STATE IMAGING DEVICE, WAFER LEVEL LENS, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2013-01-31 US disclosed
US-20130028587-A1 BLACK CURABLE COMPOSITION, LIGHT-SHIELDING COLOR FILTER FOR A SOLID-STATE IMAGING DEVICE AND METHOD OF PRODUCING THE SAME, SOLID-STATE IMAGING DEVICE, WAFER LEVEL LENS, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2013-01-31 US disclosed
US-8119311-B2 Photosensitive resin composition, light-shielding color filter and production process therefor, and image sensor FUJIFILM CORPORATION (JP) 2012-02-21 US disclosed
US-8119311-B2 Photosensitive resin composition, light-shielding color filter and production process therefor, and image sensor FUJIFILM CORPORATION (JP) 2012-02-21 US disclosed
US-8110324-B2 Photosensitive resin composition, light-shielding color filter and production process therefor, and image sensor FUJIFILM CORPORATION (JP) 2012-02-07 US disclosed
US-8110324-B2 Photosensitive resin composition, light-shielding color filter and production process therefor, and image sensor FUJIFILM CORPORATION (JP) 2012-02-07 US disclosed
US-20110172299-A1 THERAPEUTIC SUBSTITUTED CYCLOPENTANES ALLERGAN, INC. (US) 2011-07-14 US disclosed
US-20090246651-A1 PHOTOSENSITIVE RESIN COMPOSITION, LIGHT-SHIELDING COLOR FILTER AND PRODUCTION PROCESS THEREFOR, AND IMAGE SENSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090246651-A1 PHOTOSENSITIVE RESIN COMPOSITION, LIGHT-SHIELDING COLOR FILTER AND PRODUCTION PROCESS THEREFOR, AND IMAGE SENSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090246650-A1 PHOTOSENSITIVE RESIN COMPOSITION, LIGHT-SHIELDING COLOR FILTER AND PRODUCTION PROCESS THEREFOR, AND IMAGE SENSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090246650-A1 PHOTOSENSITIVE RESIN COMPOSITION, LIGHT-SHIELDING COLOR FILTER AND PRODUCTION PROCESS THEREFOR, AND IMAGE SENSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105792-A1 Photosensitive resin composition, light-shielding color filter and production process therefor, and image sensor FUJIFILM Corporation (JP) 2009-09-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110172299-A1 THERAPEUTIC SUBSTITUTED CYCLOPENTANES TUBB6, TUBB3, TUBB2A ACHE 371/4885APLNR 2998/4885MAOA 1005/4885
US-11072632-B2 Inhibitors of 17β-HSD1, 17β-HSD3 and 17β-HSD10 HSD17B11, HSD17B3, HSD17B1 ACHE 2220/4885APLNR 3951/4885MAOA 3368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.