Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | MYC | P01106 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19897461 | 0.77 | KDM4E (0.35) | HCAR2NOTUMKDM4EALDH1A1ALOX15 | |
| SCHEMBL6516964 | 0.77 | KDM4E (0.39) | HCAR2KDM4EGABRPGABRDGABRA1 | |
| SCHEMBL21895803 | 0.76 | ALDH1A1 (0.40) | KDM4EALDH1A1KMT2AHPGDL3MBTL1 | |
| SCHEMBL16132282 | 0.72 | MEN1 (0.43) | KDM4EKMT2AALOX15HPGDL3MBTL1 | |
| SCHEMBL22889774 | 0.72 | LRRK2 (0.38) | — | |
| SCHEMBL14354118 | 0.72 | KEAP1 (0.30) | — | |
| SCHEMBL21895324 | 0.71 | TSHR (0.34) | ALDH1A1POLBMAPT | |
| SCHEMBL2117045 | 0.71 | LMNA (0.50) | KDM4EALDH1A1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL6503431 | 0.71 | CYP1A2 (0.56) | KDM4EALDH1A1KMT2APKMMEN1 | |
| Hydrochloric Acid SCHEMBL11697615 | 0.70 | LMNA (0.49) | KDM4EALDH1A1KMT2AL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |