Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190129 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2PKMKMT2AALDH1A1HPGD | |
| SCHEMBL1247252 | 0.81 | PKM (0.56) | SMN1; SMN2PKMKMT2AALDH1A1MAPT | |
| SCHEMBL11620684 | 0.81 | ALDH1A1 (0.58) | SMN1; SMN2PKMKMT2AALDH1A1HPGD | |
| SCHEMBL6988984 | 0.80 | MAPT (0.41) | SMN1; SMN2KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL9793680 | 0.79 | POLB (0.50) | SMN1; SMN2PKMKMT2AALDH1A1HPGD | |
| SCHEMBL2656516 | 0.79 | POLB (0.50) | SMN1; SMN2PKMKMT2AALDH1A1HPGD | |
| SCHEMBL5369486 | 0.78 | KMT2A (0.50) | SMN1; SMN2KMT2AALDH1A1MAPTHTT | |
| SCHEMBL14540415 | 0.78 | RORC (0.46) | SMN1; SMN2PKMKMT2AALDH1A1HPGD | |
| SCHEMBL29745000 | 0.76 | ALDH1A1 (0.48) | SMN1; SMN2PKMKMT2AALDH1A1HPGD | |
| SCHEMBL505209 | 0.76 | ALDH1A1 (0.48) | SMN1; SMN2PKMKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |