Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2220068 | 0.88 | MEN1 (0.52) | KMT2AMEN1RORCHTTKDM4E | |
| SCHEMBL2220075 | 0.88 | MEN1 (0.52) | KMT2AMEN1RORCHTTKDM4E | |
| SCHEMBL13732777 | 0.85 | CYP19A1 (0.43) | KMT2AMEN1HTTALDH1A1LMNA | |
| Nitric Acid SCHEMBL28687030 | 0.83 | KMT2A (0.59) | KMT2AMEN1RORCHTTKDM4E | |
| SCHEMBL13705663 | 0.82 | SMN1; SMN2 (0.49) | KMT2AMEN1KDM4EPOLBALDH1A1 | |
| SCHEMBL7975763 | 0.81 | ALDH1A1 (0.56) | KMT2AMEN1HTTKDM4EL3MBTL1 | |
| SCHEMBL1420955 | 0.81 | PKM (0.46) | KMT2AMEN1HTTALDH1A1TRPV1 | |
| SCHEMBL11620684 | 0.81 | ALDH1A1 (0.58) | KMT2AMEN1TDP1POLBALDH1A1 | |
| SCHEMBL1247252 | 0.81 | PKM (0.56) | KMT2AMEN1HTTTDP1L3MBTL1 | |
| SCHEMBL11876061 | 0.81 | TDP1 (0.50) | KMT2AMEN1HTTKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107673976-B | The Novel synthesis technology of 2- amino -4- acetamido methyl phenyl ethers anisole | 安徽奥瑞化工有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-107673976-A | The Novel synthesis technology of the acetamido methyl phenyl ethers anisole of 2 amino 4 | 安徽奥瑞化工有限公司 | 2018-02-09 | — | — | CN | disclosed |
| US-7294716-B2 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | ALLERGAN, INC. (US) | 2007-11-13 | — | — | US | disclosed |
| EP-1644352-A1 | PROCESS FOR PREPARING ISOMERICALLY PURE PRODRUGS OF PROTON PUMP INHIBITORS | Allergan, Inc. (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005016917-A1 | PROCESS FOR PREPARING ISOMERICALLY PURE PRODRUGS OF PROTON PUMP INHIBITORS | ALLERGAN, INC. (US) | 2005-02-24 | — | — | WO | disclosed |
| US-20050038076-A1 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | ALEVIUM PHARMACEUTICALS, INC. | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038076-A1 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | SI, ATP6AP1, HRH2 | KMT2A 1672/4885MEN1 2438/4885RORC 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.