Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 3/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951528 | 0.80 | POLB (0.39) | POLB | |
| SCHEMBL29953293 | 0.79 | MAP4K4 (0.42) | POLBMAP4K4MKNK1MKNK2PDE4A | |
| SCHEMBL29958512 | 0.78 | HCAR3 (0.40) | POLBKMOPDE4APDE4BPDE4C | |
| SCHEMBL29955130 | 0.77 | PDGFRB (0.35) | POLBMAP4K4 | |
| SCHEMBL29955617 | 0.77 | POLB (0.39) | POLB | |
| SCHEMBL30531824 | 0.75 | POLB (0.49) | POLBKMOMKNK1MKNK2PDE4A | |
| SCHEMBL29950803 | 0.72 | POLB (0.37) | POLBMKNK1MKNK2PDE4APDE4B | |
| SCHEMBL29951667 | 0.71 | POLB (0.36) | POLBMKNK1MKNK2PDE4APDE4B | |
| SCHEMBL29957854 | 0.71 | SCD (0.36) | POLBKMOMKNK1MKNK2 | |
| SCHEMBL29955753 | 0.70 | SCD (0.42) | POLBKMOMKNK1MKNK2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |