Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958512 | 0.88 | HCAR3 (0.40) | PDE4DPDE4BPDE4APDE4CPOLB | |
| SCHEMBL29956395 | 0.82 | HPGDS (0.40) | PDE4DPDE4BPDE4APDE4CPOLB | |
| SCHEMBL29953815 | 0.79 | POLB (0.39) | MAP4K4PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL29951528 | 0.75 | POLB (0.39) | IRAK4POLB | |
| SCHEMBL29956159 | 0.74 | MAP4K4 (0.42) | MAP4K4PARP10PDE4DPDE4BPDE4A | |
| SCHEMBL29956602 | 0.74 | PARP10 (0.50) | MAP4K4PARP10PDE4DPDE4BPDE4A | |
| SCHEMBL29955617 | 0.72 | POLB (0.39) | POLB | |
| SCHEMBL29955972 | 0.72 | PDE4A (0.46) | MAP4K4PARP10PDE4DPDE4BPDE4A | |
| SCHEMBL29951714 | 0.72 | MKNK1 (0.44) | MAP4K4PARP10PDE4DPDE4BPDE4A | |
| SCHEMBL29953167 | 0.71 | PDE4B (0.52) | MAP4K4PARP10PDE4DPDE4BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |