Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 5/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955270 | 0.90 | HCAR3 (0.57) | HCAR3CNR2HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL19630947 | 0.82 | HCAR3 (0.54) | HCAR3HPGDSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3299277 | 0.79 | ALDH1A1 (0.44) | HCAR3ALDH1A1KDM4EGAAHDAC1 | |
| SCHEMBL6361877 | 0.79 | CYP2C19 (0.53) | HCAR3HPGDSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL28782093 | 0.79 | HCAR3 (0.60) | HCAR3ALDH1A1KDM4E | |
| SCHEMBL29953824 | 0.77 | HCAR3 (0.41) | HCAR3TLR8HRH4HDAC1L3MBTL1 | |
| SCHEMBL10604098 | 0.77 | HCAR3 (0.59) | HCAR3CNR2TLR8HPGDSMN1; SMN2 | |
| SCHEMBL22795638 | 0.76 | RAB9A (0.61) | HCAR3CNR2TLR8HPGDSMN1; SMN2 | |
| Bromide SCHEMBL10609035 | 0.76 | HCAR3 (0.58) | HCAR3CNR2TLR8HPGDSMN1; SMN2 | |
| SCHEMBL5493605 | 0.75 | LMNA (0.43) | HPGDSMN1; SMN2ALDH1A1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |