Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951388 | 0.93 | ALDH1A1 (0.50) | ALDH1A1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL29953059 | 0.86 | NPSR1 (0.47) | ALDH1A1LMNANPSR1PTGS1GRM5 | |
| SCHEMBL29953701 | 0.86 | NPSR1 (0.47) | ALDH1A1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL15331429 | 0.84 | DHODH (0.40) | ALDH1A1LMNANPSR1KMT2APOLB | |
| SCHEMBL11726388 | 0.83 | PTGS2 (0.46) | ALDH1A1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL29952180 | 0.81 | ALDH1A1 (0.42) | ALDH1A1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL15330528 | 0.81 | NPC1 (0.43) | ALDH1A1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL15331449 | 0.81 | NPC1 (0.47) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL15332602 | 0.80 | ALDH1A1 (0.40) | ALDH1A1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL2557352 | 0.79 | CA1 (0.39) | ALDH1A1LMNANPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |