Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 5/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369216 | 0.75 | PSMD14 (0.48) | PSMD14GRM4ADORA3ADORA2AKDR | |
| SCHEMBL2066259 | 0.75 | PSMD14 (0.48) | PSMD14KCNMA1GRM4ADORA3ADORA2A | |
| SCHEMBL3219684 | 0.73 | PSMD14 (0.47) | PSMD14GRM4ADORA3ADORA2AKDR | |
| Potassium SCHEMBL3219697 | 0.73 | PSMD14 (0.47) | PSMD14GRM4ADORA3ADORA2AKDR | |
| SCHEMBL12006266 | 0.72 | PARP1 (0.50) | PARP1LMNA | |
| SCHEMBL12479995 | 0.71 | PBRM1 (0.54) | PSMD14GRM4CYP2C19NPC1L3MBTL1 | |
| SCHEMBL29601281 | 0.71 | PBRM1 (0.54) | PSMD14GRM4CYP2C19NPC1L3MBTL1 | |
| SCHEMBL29951554 | 0.71 | MAP4K1 (0.39) | PARP1KDM4E | |
| SCHEMBL569155 | 0.71 | AXL (0.50) | PSMD14KCNMA1GRM4KDRFLT3 | |
| SCHEMBL22510135 | 0.71 | PSMD14 (0.48) | PSMD14GRM4HSP90AA1L3MBTL1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |