Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 2/20 | 0.35 |
| ▸ | HIPK1 | Q86Z02 | 2/20 | 0.35 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.35 |
| ▸ | HIPK3 | Q9H422 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953859 | 0.71 | PSMD14 (0.44) | PARP1KDM4E | |
| SCHEMBL29953852 | 0.71 | AXL (0.43) | MAP4K1PARP1CLK4KDM4EPIM1 | |
| SCHEMBL29951236 | 0.68 | MEN1 (0.43) | ALDH1A1MEN1KMT2ARAB9ATDO2 | |
| SCHEMBL29953398 | 0.68 | MEN1 (0.43) | ALDH1A1MEN1KMT2ARAB9APARP1 | |
| SCHEMBL31626386 | 0.67 | PARP1 (0.47) | ALDH1A1MEN1KMT2ARAB9APARP1 | |
| SCHEMBL21309091 | 0.67 | MGLL (0.58) | ALDH1A1MEN1KMT2ARAB9APARP1 | |
| SCHEMBL31626694 | 0.67 | MGLL (0.58) | ALDH1A1MEN1KMT2ARAB9APARP1 | |
| SCHEMBL23535594 | 0.66 | KDM4E (0.49) | ALDH1A1MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL29954734 | 0.66 | SQOR (0.50) | ALDH1A1MEN1KMT2ARAB9ATDO2 | |
| SCHEMBL1753930 | 0.65 | MEN1 (0.59) | ALDH1A1MEN1KMT2ARAB9APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |