Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 4/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.47 |
| ▸ | TTR | P02766 | 3/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2413286 | 1.00 | LPL (0.47) | LPLLIPGTTRENPP2KDM4E | |
| SCHEMBL18015403 | 0.82 | TTR (0.47) | LPLLIPGTTRENPP2CA2 | |
| SCHEMBL3790779 | 0.81 | LPL (0.52) | LPLLIPGENPP2CA2CA1 | |
| SCHEMBL16702930 | 0.79 | TTR (0.42) | TTRENPP2CA2 | |
| SCHEMBL16576629 | 0.79 | TTR (0.42) | LPLLIPGTTRENPP2KDM4E | |
| SCHEMBL21501435 | 0.79 | ENPP2 (0.46) | LPLLIPGTTRENPP2ALDH1A1 | |
| SCHEMBL21179834 | 0.79 | HTT (0.43) | ALDH1A1L3MBTL1 | |
| SCHEMBL31035574 | 0.78 | TTR (0.44) | LPLLIPGTTRENPP2CA2 | |
| SCHEMBL21179848 | 0.78 | L3MBTL1 (0.42) | TTRALDH1A1L3MBTL1 | |
| SCHEMBL22683555 | 0.78 | ESR1 (0.50) | LPLLIPGENPP2CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |