Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21179848 | 0.85 | L3MBTL1 (0.42) | HTTCYP3A4P2RX7CYP1A2CYP2C9 | |
| SCHEMBL29337714 | 0.80 | HTT (0.47) | HTTCYP3A4P2RX7CYP1A2CYP2D6 | |
| SCHEMBL29953894 | 0.79 | LPL (0.47) | ALDH1A1L3MBTL1 | |
| SCHEMBL2413286 | 0.79 | LPL (0.47) | ALDH1A1L3MBTL1 | |
| SCHEMBL754563 | 0.78 | CYP3A4 (0.46) | HTTCYP3A4P2RX7CYP1A2CYP2D6 | |
| SCHEMBL21179833 | 0.77 | SMN1; SMN2 (0.33) | HTTCYP3A4P2RX7CYP1A2CYP2D6 | |
| SCHEMBL2910835 | 0.74 | HTT (0.71) | HTTCYP3A4P2RX7CYP2D6CYP2C19 | |
| SCHEMBL30259918 | 0.74 | HTT (0.71) | HTTCYP3A4P2RX7CYP2D6CYP2C19 | |
| SCHEMBL1750408 | 0.73 | TSHR (0.50) | HTTCYP3A4P2RX7ALDH1A1MEN1 | |
| SCHEMBL17914676 | 0.72 | ALDH1A1 (0.62) | P2RX7NPC1ALDH1A1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10357036-B2 | Compounds for controlling arthropods | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10357036-B2 | Compounds for controlling arthropods | DDT, ACHE, NISCH | HTT 175/4885CYP3A4 319/4885P2RX7 2396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.